Preventing Loss of Independence through Exercise in Persons with Dementia (PLIE)
This study tests a novel, integrative exercise program for individuals with dementia called Preventing Loss of Independence through Exercise (PLIÉ). PLIÉ was designed to integrate effective exercises from various cultural traditions. It focuses on building and maintaining the capacity to perform basic functional movements combined and integrated with increasing body awareness and encouraging social engagement.
The current trial is following up on a pilot study of PLIÉ that suggested that this integrative exercise intervention not only slowed cognitive decline but improved cognitive function. It studies changes in the brain using MRI in veterans and non-veterans with mild cognitive impairment, funded by the Department of Defense.
Study Investigators
- Principal Investigator: Linda Chao, PhD, UCSF Professor in the Department of Radiology and Biomedical Imaging and in the Department of Psychiatry
- Co-Investigators: Wolf Mehling, MD and Margaret A. Chesney, PhD, UCSF Osher Center for Integrative Medicine
To enroll in this study, please contact:
Michele Woo
Research Health Science Specialist
Preventing Loss of Independence through Exercise (PLIÉ) Research Study
San Francisco VA Medical Center
PLIÉ Line: (844) 366-6866
