MOTION: Multi-domain Online Therapeutic Investigation Of Neurocognition
The goal of our study is to compare three different online behavioral interventions aimed at improving function and quality of life in people with mild to moderate memory loss.
You may be eligible if:
- You are 55 years old or older
- You have been diagnosed with Mild Cognitive Impairment or you think your memory has noticeably declined over the past year or so
- You are fluent in English
- You have a wireless internet connection at home
- You are willing to travel to the SFVA Medical Center or UCLA for in-person assessments
Participants are not eligible if:
- You have a severe visual or hearing impairment that would limit your ability to see or hear the instructor's directions on your computer or tablet
- You are participating in another research study
- You are claustrophobic, have metal implants not compatible with MRI, or have any other conditions that do not allow for an MRI
Participation summary:
- You will be active in this study for a total of 35 hours over 9 months.
- We will ask you a series of questions and perform a cognitive assessment to assess your eligibility over phone/Zoom (15-30 mins)
Assessment 1, at your chosen site (SFVA Medical Center or UCLA): 2-3 hours
- You will take some in-person additional tests of your physical functioning (such as walking) and cognitive functioning (such as memory).
- You will then have a brain scan called an MRI.
- You will be compensated $50
12-Week Course
- You will be randomly assigned to one of three online classes: a Mindful Movement Class, a Tai Chi class, or a Health and Wellness Education seminar on healthy cognitive aging
- You will participate in your assigned class from the comfort of your home for 60 minutes, 2 days per week for 12 weeks
Assessment 2 at your chosen site (SFVA Medical Center or UCLA): 2-3 hours
- Immediately after you finish your online course, you will come in person to your chosen site and repeat the tests of your physical and cognitive function
- You will complete your final MRI scan
- You will be compensated $100
Assessment 3 at your chosen site (SFVA Medical Center or UCLA): 1-2 hours
- 6 months after you finish your online course, you will come in person to your chosen site and repeat the tests of your physical and cognitive function
- You will be compensated $50
You will additionally be compensated up to $150 for parking and travel expenses, for a up to $350 of total compensation.
For general information about the study, visit our website here.
If you would like us to contact you with more information about the study, complete our survey here.
Study Investigators
- Principal Investigator: Linda Chao, PhD, UCSF and the San Francisco VA Medical Center
- Co-Investigators: Wolf Mehling, MD, Margaret Chesney, PhD, and Deborah Barnes, PhD, UCSF Osher Center for Integrative Health, Helen Lavretsky, MD, MS, UCLA