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Current Research Projects

Mind-Body Based Modalities Traditional Chinese Medicine Massage & Body Based Therapies Herbal Medicine & Dietary Supplements Observational Studies

 

Project Name and Description Principal Investigator Source Dates &
Awards
Status
Mind-Body Based Modalities
MBSR and Early Stage HIV
Three linked studies of the effects of meditation based stress reduction and education in early HIV on physical health and psychological well-being.

Susan Folkman, PhD; Co-PI: Rick Hecht, MD

Contact: Patricia Moran

Website: Staying Well
NIH/
NCCAM
$5,995,316 7/1/04- 6/30/09 Open July 2005
P01 I. Clinical Trial of MBSR and Education in Early HIV
This is a 330 person randomized controlled trial of mediation based stress reduction and education in early HIV that will assess the effects on psychological well being and disease course.
See abstract

Director: Rick Hecht, MD; Co-Director: Donald Abrams, MD

Contact: Patricia Moran

Website: Staying Well
NIH/
NCCAM

See Program Project

Open July 2005
P01 II. MBSR, Education, and Stress Arousal
This project will perform detailed studies in a subset of participants in the P01 trial of stress-related adaptive and maladaptive cognitive and affective mechanisms through which MBSR and education may influence neuroendocrine and autonomic nervous system activity. 
See abstract

Director: Susan Folkman, PhD; Co-Director: Elissa Epel, PhD

Contact: Patricia Moran

Website: Staying Well
NIH/
NCCAM
See Program Project Sub-study of Clnical Trial of MBSR in Early HIV
P01 III. MBSR, Education, and the Immune System
This project will perform detailed studies in a subset of participants in the P01 trial to determine the effects of MBSR and education on the immune system, including NK cell numbers and function, T cell activation, innate immune responses to HIV, cytokine production and expression of co-receptors for HIV cell entry (CCR5).
See abstract

Director: Jay Levy, MD; Co-Director: Margaret Kemeny, PhD

Contact: Patricia Moran

Website: Staying Well
NIH/
NCCAM

See Program Project

Sub-study of Clnical Trial of MBSR in Early HIV
R21 Yoga, Meditation and Health: Efficacy of Yoga Based Lifestyle Intervention for Pre-Diabetes
This is a pilot randomized, controlled trial performed as part of a planning grant to establish an international center for collaborative research on yoga with SVYASA in Bangalore India. It will test whether yoga is associated with lower fasting glucose and improved glucose tolerance in pre-diabetics. Secondary outcomes include weight loss, blood pressure, and insulin sensitivity.
See abstract

PI: Rick Hecht, MD; Co PI's: Morris Schambelan, MD; Adam Burke, PhD, MPH, LAc (SFSU); Nagarathna R., MD, FRCP (SVYASA); Nagendra H.R., ME, PhD (SVYASA); Srikanta S., MD, FEDM (SVYASA) D

Contact: Stephanie Maurer

NIH/
NCCAM
$256,980 9/22/03 - 3/31/05 Closed
Yoga, Meditation and Health: Yoga and HIV
This is a pilot randomized controlled trial performed as part of a planning grant to establish an international center for collaborative research on yoga with SVYASA in Bangalore India. It will study people with HIV to provide preliminary data about whether yoga is associated with improved mood, decreased stress, and higher CD4 T-cell counts.
See abstract

Frederick Hecht, MD; Adam Burke, PhD, MPH, LAc (SFSU); Nagarathna R., MD, FRCP (SVYASA); Nagendra H.R., ME, PhD (SVYASA)

Contact: Stephanie Maurer

NIH/
NCCAM

07/15/2004 (Linked to grant above)

Closed
Yoga Study for Back Pain
This is a randomized, controlled trial of the effects of Iyengar Yoga for patients with chronic idiopathic low back pain focusing on clinical and physiological outcomes and health care utilization.
See abstract

PI: Bradly Jacobs, MD, MPH

Contact:
Stephanie Maurer

Mt. Zion
Health Fund
$52,000 12/01/01-12/31/03 Closed
Efficacy of Yoga for Self-Management of Dyspnea in COPD
This is a randomized, controlled trial of the efficacy of yoga, especially yoga breathing exercises, on COPD outcomes.
See abstract

PI: Virginia Carrieri-Kohlman, DNSc, RN

Contact:
DorAnne Dyspnea

NIH/
NCCAM

$371,625 9/15/02-05/31/04

Closed
K23 Mind-Body Therapies to Prevent Chronic Low Back-Pain
This is a career development award that will develop and validate a brief prediction tool for primary care clinics to assess psycho-social risk factors for acute and chronic low back pain, and will perform an assessment of whether specific mind-body therapies alter these risk factors.
See abstract
PI:Wolf Mehling, MD NIH/
NCCAM

Mt. Zion
Health Fund
7/1/05-6/30/10, $608,466
2/1/07-1/31/09,
$100,000
Restricted Enrollment
Treating Depression with Pranayama: A Feasibility Study in Older Adults
This study will explore whether pranayama, a series of breathing exercises within the yoga tradition of India, can be learned and practiced regularly by older adults who suffer from depression.
See abstract

PI:Sudha Prathikanti, MD, Co-PI: Owen Wolkowitz, MD

Contact:
Rheinila Fernandez
415-206-5130

NIMH

$6,500

Closed
Focus Study: R21 A Mindfulness Approach to HIV Treatment Side Effects
This is a randomized controlled trial to provide preliminary evidence of the efficacy of Mindfulness-Based Stress Reduction (MBSR) intervention to remediated side effects and side effect - related distress from antiretroviral therapy in HIV treatement.
See abstract

PI:Mallory Johnson, PhD Co-PI: Rick Hecht, MD

Contact: Eunice Stephens

NCCAM $400,000 Open
Biofeedback for Functional Constipation: Efficacy and Predicitive Factors of Success
This is a pilot study to examine the efficacy of anorectal biofeedback therapy for functional constipation secondary to pelvic floor dyssynergia.
See abstract

PI: Madhulika Varma. MD Research Associate: Taryn Patterson

Contact: Taryn Patterson

REAC

3/1/05-2/28/06 15,000

Open
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Project Name and Description Principal Investigator Source Dates & Awards Status
Traditional Chinese Medicine
Central Processing of Acupuncture Anaglesia in Myofascial Pain: a Brain fMRI Study
This is a pilot study to determine whether acupuncture activates/decreases specific areas of the brain cortex with pain inhibitory function, and evaluate short-term pain reduction using VAS pain rating to mechanical pressure on the masseter muscle.
See abstract

Greg Goddard, DDS

Contact:
Greg Goddard

Mt. Zion
Health Fund
$35,000 Closed
Traditional Chinese Medicine and Epidemiologic Approaches in Breast Cancer
This will explore the feasibility of generating TCM classifications using a standardized method among women who were newly diagnosed with breast cancer in the Bay Area.
See abstract

Marion M. Lee, PhD

Contact:
Marion Lee

U.S. Army
Medical
Research
and Materiel
Command.
Award #
DAMD17-
00-1-0611

$55,000 8/31/03-9/30/04

Closed
Acupuncture for the Treatment of Chronic Sinusitis
This randomized, controlled, single-blinded study will evaluate the effect of adding acupuncture to standard medical treatment on indicators of chronic sinusitis, namely quality of life, as measured by radiographic imaging, physical examination, and self-reported symptoms and disability. 
See abstract

Co-PIs:  Andrew N. Goldberg, MD, MSCE; Joseph S. Acquah, OMD, LAc

Contact:
Andrew Goldberg

Dept. Funding N/A Open
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Project Name and Description Principal Investigator Source Dates & Awards Status
Massage & Body Based Therapies
Chemotherapy Regimen and Fatigue: Touch Therapy - CRAFT
This is a study of the effects of massage on cancer-related fatigue.
See abstract

Andy Avins, MD, MPH

Contact:
Stephanie Maurer

NIH/
NCCAM
$356,981 3/1/01 - 12/31/03 No cost extension 2004; Supplement 2004-2005 Closed
Randomized Controlled Trial of Breath Therapy for Patients with Chronic Low Back Pain- pilot
This is a pilot randomized, controlled trial of breath therapy (BT) for patients suffering from chronic low back pain. Primary outcome measures are back pain ratings and standardized functional disability questionnaires.
See abstract

Wolf Mehling, MD

Contact:
Wolf Mehling

Mt. Zion
Health Fund

$48,748 1/1/03-12/31/03

Closed
Pilot Evaluation of Perioperative Integrative Medicine Service (PIMS)- for cancer surgery patients at Mount Zion Hospital
This is a pilot randomized, controlled trial of a perioperative integrative medicine service (PIMS) for cancer surgery patients. It will evaluate clinical symptoms, patient satisfaction, and health care utilization.
See abstract
Bradly Jacobs, MD, MPH, PI Wolf Mehling, MD, PI Mt. Zion
Health Fund
$91,260 3/1/07-
6/30/07
Closed
back to top
Project Name and Description Principal Investigator Source Dates & Awards Status
Herbal Medicines & Dietary Supplements
RO1 Efficacy of Saw Palmetto Extract in Benign Prostatic Hyperplasia
A randomized controlled trial of the use of saw palmetto for the prevention of prostate disease.
See abstract

Andy Avins, MD, MPH

Contact:
Andrew Avins

NIH/NCC,
NIDDK
$1,736,000 1999-2002 Closed
KO8 Adverse Reactions to Herbs
This is a career development award that will perform secondary data analyses of Kaiser data  to identify potential adverse effects from herb-drug interactions.
See abstract

Steve Bent , MD

Contact:
Amy Padula

NIH/
NCCAM

12/16/02- 11/30/07 $608,250 direct and indirect

N/A
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Project Name and Description Principal Investigator Source Dates & Awards Status
Observational Studies
CHAI Study: Coping, HIV, and Affect Interview Study
This is an observational study of emotions, coping, and health in those newly diagnosed with HIV. 
See abstract

Judith Moskowitz, PhD

Contact:
Stephanie Maurer

NIH/
NIMH
$2,969,069 Open
Positive Affect and Stress Hormones in Newly Diagnosed HIV+ Men Supplement
The study will explore one set of physiological correlates of positive affect, stress related hormones, which may mediate the associations with disease progression in people with HIV.

Judith Moskowitz, PhD; Co-PI: Elissa Epel, PhD

Contact:
Stephanie Maurer

Mt. Zion
Health Fund

$31,232 Funding starting July 2004

Sub-study of Role of Positive Affect in Adjustment to HIV
Care Preferences at End of Life
This is a study of end-of-life patients and their family caregivers regarding their preferences for care, care actually utilized, and the effects of patient and caregiver mood on preferences and choices.
See abstract

Susan Folkman, PhD

Contact:
Patricia Moran

NIH/
NINR
$1,383,419 9/1/02-6/30/05 Closed
K08 Depression, Stress & Health: Role of Anabolic Hormones
This is a career development award t o examine whether the balance between cortisol and
anabolic hormones may be a mediating pathway leading from chronic stress to mental and physical illness.

Elissa Epel, PhD

Contact:
Elissa Epel

NIH/
NIMH

$773,975 9/1/02-8/30/07

Closed
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Updated: January 31, 2007
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